Article
Capsular hyaluronic acid of group A streptococci hampers their invasion into human pharyngeal epithelial cells.
Microbial pathogenesis - 1 Aug 1999
Kawabata S, Kuwata H, Nakagawa I, Morimatsu S, Sano K, Hamada S
Abstract excerpt
Group A streptococci (GAS) cause various diseases, from uncomplicated noninvasive, to severe invasive infections. Capsular hyaluronic acid (HA) is known to resist phagocytosis, however, interaction between HA and epithelial cells have not been clearly understood. In this study, both HA-producing wild strains and HA-nonproducing mutants were employed to examine their invasiveness into confluent cultures of HEp-2,...
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