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Article

The luxS gene of Streptococcus pyogenes regulates expression of genes that affect internalization by epithelial cells.

Infection and immunity - 1 Oct 2003

Marouni Mehran J, Sela Shlomo

Abstract excerpt

The gram-positive pathogen Streptococcus pyogenes was recently reported to possess a homologue of the luxS gene that is responsible for the production of autoinducer 2, which participates in quorum sensing of both gram-positive and gram-negative bacteria. To test the effect of LuxS on streptococcal internalization, a LuxS mutant was constructed in strain SP268, an invasive M3 serotype. Functional analysis of the...

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Identifiers

PMID: 14500483
DOI: 10.1128/IAI.71.10.5633-5639.2003
PMCID: PMC201110

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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