Article
Introduction of the emm6 gene into an emm-deleted strain of Streptococcus pyogenes restores its ability to resist phagocytosis.
Research in microbiology - 1 Jan 2000
Perez-Casal J, Caparon M G, Scott J R
Abstract excerpt
To complete the formal proof that the M protein functions to protect the group A streptococcus from phagocytosis and to lay the groundwork for the molecular genetic dissection of this major virulence factor, we have reintroduced a wild-type allele of the M protein gene (emm) into the chromosome o...
Topics
- Alleles
- Bacterial Proteins
- Blotting, Southern
- Blotting, Western
- Genetics, Microbial
- In Vitro Techniques
- Kanamycin Resistance
- Phagocytosis
- Plasmids
- Recombination, Genetic
- Restriction Mapping
- Streptococcus pyogenes