Article
Critical role of the group A streptococcal capsule in pharyngeal colonization and infection in mice.
Proceedings of the National Academy of Sciences of the United States of America - 6 Dec 1994
Wessels M R, Bronze M S
Abstract excerpt
To study the role of the group A streptococcal capsule in pharyngeal colonization, we used two acapsular mutants derived from a type 24 strain of group A Streptococcus by transposon mutagenesis. One mutant had a stable acapsular phenotype due to a transposon-associated chromosomal deletion of ess...
Topics
- Animals
- Antigens, Bacterial
- Bacterial Outer Membrane Proteins
- Bacterial Proteins
- Carrier Proteins
- Cell Wall
- Chromosome Deletion
- Chromosomes, Bacterial
- Female
- Genes, Bacterial
- Genes, Synthetic
- Mice
- Mice, Inbred Strains
- Mutagenesis, Insertional
- Phagocytosis
- Pharynx
- Phenotype
- Streptococcal Infections