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Article

Critical role of the group A streptococcal capsule in pharyngeal colonization and infection in mice.

Proceedings of the National Academy of Sciences of the United States of America - 6 Dec 1994

Wessels M R, Bronze M S

Abstract excerpt

To study the role of the group A streptococcal capsule in pharyngeal colonization, we used two acapsular mutants derived from a type 24 strain of group A Streptococcus by transposon mutagenesis. One mutant had a stable acapsular phenotype due to a transposon-associated chromosomal deletion of essential capsule synthetic genes, while the second mutant could revert to the encapsulated phenotype at a low frequency...

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Identifiers

PMID: 7991612
DOI: 10.1073/pnas.91.25.12238
PMCID: PMC45412

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Source receipt: pubmed, retrieved 7 Sept 2026.

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