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Article

Identification of <i>csrR/csrS</i>, a genetic locus that regulates hyaluronic acid capsule synthesis in group A <i>Streptococcus</i>

1 Oct 1998

Abstract excerpt

The hyaluronic acid capsule of group A Streptococcus (GAS) is an important virulence factor, but little is known about mechanisms that regulate capsule expression. Transposon Tn916 mutagenesis of the poorly encapsulated M-type 3 GAS strain DLS003 produced a transconjugant that exhibited a mucoid colony morphology, reflecting increased hyaluronic acid capsule production. Analysis of chromosomal DNA sequence...

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PMID: 9786197
DOI: 10.1046/j.1365-2958.1998.01057.x

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Identification of <i>csrR/csrS</i>, a genetic locus that regulates hyaluronic acid capsule synthesis in group A <i>Streptococcus</i>PMID 9786197Read ↗

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