Article
The role played by the group A streptococcal negative regulator Nra on bacterial interactions with epithelial cells
1 Apr 2001
Abstract excerpt
Group A streptococci (GAS) specifically attach to and internalize into human epithelial host cells. In some GAS isolates, fibronectin-binding proteins were identified as being responsible for these virulence traits. In the present study, the previously identified global negative regulator Nra was shown to control the binding of soluble fibronectin probably via regulation of protein F2 and/or SfbII expression in...
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