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Article

Characterization of a mouse-passaged, highly encapsulated variant of group A streptococcus in in vitro and in vivo studies.

The Journal of infectious diseases - 1 Dec 2000

Ravins M, Jaffe J, Hanski E, Shetzigovski I, Natanson-Yaron S, Moses A E

Abstract excerpt

JRS4(HE), a highly encapsulated, mouse-passaged variant of group A streptococcal strain JRS4, was characterized. The mucoid phenotype of JRS4(HE) was preserved after extensive passage in vitro. The level and size of csrRS transcript in JRS4(HE) was similar to that of JRS4, yet JRS4(HE) expressed high levels of has and sagA and exhibited an increased activity of streptolysin S. These findings indicate that the...

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PMID: 11069243
DOI: 10.1086/317635

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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