Article
Characterization of a two-component system in Streptococcus pyogenes which is involved in regulation of hyaluronic acid production.
The Journal of biological chemistry - 19 Feb 1999
Bernish B, van de Rijn I
Abstract excerpt
Hyaluronic acid production by group A streptococci is regulated by transcriptional control. In this study, transposon mutagenesis of an unencapsulated strain yielded an encapsulated mutant. Two genes homologous to sensors and response regulators of bacterial two-component systems were identified downstream of the transposon insertion. Inactivation of the putative sensor gene, csrS, in three different...
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