Article
Microsatellite instability in germ cell tumors of the testis and ovary.
Gynecologic oncology - 1 Oct 2000
Faulkner S W, Friedlander M L
Abstract excerpt
OBJECTIVES: Widespread replication-type error (RER) is a genetic alteration that has been observed in many different neoplasms and has been associated with defective DNA repair activity. There are conflicting data regarding the role that this type of genetic instability plays in the development and progression of adult germ cell tumors. METHODS: Universal amplification was performed on 104 paired specimens of...
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