Article
Molecular genetic changes in human male germ cell tumors.
Laboratory investigation; a journal of technical methods and pathology - 1 Nov 1995
Lothe R A, Peltomäki P, Tommerup N, Fosså S D, Stenwig A E, Børresen A L, Nesland J M
Abstract excerpt
BACKGROUND: An isochromosome for the short arm of chromosome 12, i(12p), is the most common and characteristic cytogenetic aberration in testicular germ cell tumors. Little is known about the molecular genetic abnormalities of these neoplasms. EXPERIMENTAL DESIGN: A total of 32 loci were studied in DNA from 31 primary testicular germ cell tumors and compared with corresponding normal DNA. The loci map to 17...
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