Article
Replication error-type genetic instability at 1q42-43 in human male germ cell tumors.
Cancer research - 1 Aug 1994
Murty V V, Li R G, Mathew S, Reuter V E, Bronson D L, Bosl G J, Chaganti R S
Abstract excerpt
The replication error phenotype, recognized as microsatellite sequence alterations, has recently been suggested to be associated with hereditary nonpolyposis colorectal cancer and other types of sporadic tumors. We examined paired tumor-normal DNAs from 69 human male germ cell tumors for somatic instability at the 1q42-43 region. Analysis of a variable number of tandem repeats marker (D1S74) and 3 (CA)n type...
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