Article
A role for GATA5 in Xenopus endoderm specification.
Development (Cambridge, England) - 1 Oct 2000
Weber H, Symes C E, Walmsley M E, Rodaway A R, Patient R K
Abstract excerpt
The endoderm gives rise to the gut and tissues that develop as outgrowths of the gut tube, including the lungs, liver and pancreas. Here we show that GATA5, a zinc-finger transcription factor, is expressed in the yolk-rich vegetal cells of Xenopus embryos from the early gastrula stage onwards, when these cells become committed to form endoderm. At mid-gastrula stages, GATA5 is restricted to the sub-blastoporal...
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