Article
Zebrafish endoderm formation is regulated by combinatorial Nodal, FGF and BMP signalling.
Development (Cambridge, England) - 1 Jun 2006
Poulain Morgane, Fürthauer Maximilian, Thisse Bernard, Thisse Christine, Lepage Thierry
Abstract excerpt
In the zebrafish embryo, the mesoderm and endoderm originate from common precursors and segregate during gastrulation by mechanisms that are largely unknown. Understanding how the signalling pathways that regulate endoderm and mesoderm formation interact is crucial to understanding how the germ layers are established. Here, we have analysed how the FGF and BMP pathways interact with Nodal signalling during the...
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