Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

An IL6 promoter polymorphism is associated with a lifetime risk of development of Kaposi sarcoma in men infected with human immunodeficiency virus.

Blood - 1 Oct 2000

Foster C B, Lehrnbecher T, Samuels S, Stein S, Mol F, Metcalf J A, Wyvill K, Steinberg S M, Kovacs J, Blauvelt A, Yarchoan R, Chanock S J

Abstract excerpt

Kaposi sarcoma (KS) is an angioproliferative inflammatory condition that occurs commonly in patients infected with human immunodeficiency virus (HIV). Inflammatory cytokines and growth factors promote the development of KS. Because physiologically important cytokine polymorphisms modulate host inflammatory responses, we investigated the association between KS and common regulatory polymorphisms in 5...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to HIV Infections
Share to Interleukin-1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Interleukin 1 Receptor Antagonist Protein

Share to Interleukin-6

Share to Lymphotoxin-alpha

Share to Sarcoma, Kaposi

Share to Sialoglycoproteins

Share to Tumor Necrosis Factor-alpha

Source

Identifiers

PMID: 11001912

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An IL6 promoter polymorphism is associated with a lifetime risk of development of Kaposi sarcoma in men infected with human immunodeficiency virus.PMID 11001912Read ↗

An IL-8 gene promoter polymorphism is associated with the risk of the development of AIDS-related Kaposi's sarcoma: a case-control study.Semantic proximity Read ↗

The interleukin-6-174 promoter polymorphism is associated with a risk of development of Kaposi's sarcoma in renal transplant recipients.Semantic proximity Read ↗

Associations of classic Kaposi sarcoma with common variants in genes that modulate host immunity.Semantic proximity Read ↗

Familial Kaposi's Sarcoma in HHV8 infected subjects presenting the G-174C allele of the IL-6 promoter: a possible role for EBV?Semantic proximity Read ↗

Variant genotypes of FcγRIIIA influence the development of Kaposi's sarcoma in HIV-infected menSemantic proximity Read ↗

Variant genotypes of FcgammaRIIIA influence the development of Kaposi's sarcoma in HIV-infected men.Semantic proximity Read ↗

Genetic variation in proinflammatory cytokines IL6, IL6R, TNF-region, and TNFRSF1A and risk of breast cancer.Semantic proximity Read ↗

Kaposi's sarcoma-associated human herpesvirus-8 encodes homologues of macrophage inflammatory protein-1 and interleukin-6Semantic proximity Read ↗

Molecular Mimicry of Human Cytokine and Cytokine Response Pathway Genes by KSHVSemantic proximity Read ↗

Interleukin-6 promoter polymorphism (-174 G/C) in Caucasian German patients with systemic lupus erythematosusSemantic proximity Read ↗

Haplotype structure of inflammatory cytokines genes (IL1B, IL6 and TNF/LTA) in US Caucasians and African Americans.Semantic proximity Read ↗

Differential distribution of allelic variants in cytokine genes among African Americans and White Americans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.