Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Variant genotypes of FcgammaRIIIA influence the development of Kaposi's sarcoma in HIV-infected men.

Blood - 1 Apr 2000

Lehrnbecher T L, Foster C B, Zhu S, Venzon D, Steinberg S M, Wyvill K, Metcalf J A, Cohen S S, Kovacs J, Yarchoan R, Blauvelt A, Chanock S J

Abstract excerpt

Disturbances in inflammatory cytokine production and immune regulation coupled with human herpesvirus-8 (HHV-8) infection underlie the current understanding of the pathogenesis of Kaposi's sarcoma (KS), the most common HIV-associated malignancy. The low affinity Fc gamma receptors (FcgammaR) for IgG link humoral and cellular immunity by mediating interaction between antibodies and effector cells, such as...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acquired Immunodeficiency Syndrome
Share to Antibodies, Viral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Herpesvirus 8, Human

Share to Polymerase Chain Reaction

Share to Polymorphism, Genetic

Share to Receptors, IgG

Share to Sarcoma, Kaposi

Source

Identifiers

PMID: 10733511

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Variant genotypes of FcgammaRIIIA influence the development of Kaposi's sarcoma in HIV-infected men.PMID 10733511Read ↗

Variant genotypes of FcγRIIIA influence the development of Kaposi's sarcoma in HIV-infected menSemantic proximity Read ↗

FcgammaRIIa genotype predicts progression of HIV infection.Semantic proximity Read ↗

High affinity allele for the gene of FCGR3A is risk factor for HIV infection and progression.Semantic proximity Read ↗

An IL6 promoter polymorphism is associated with a lifetime risk of development of Kaposi sarcoma in men infected with human immunodeficiency virus.Semantic proximity Read ↗

The role of Fc receptors in HIV infection and vaccine efficacy.Semantic proximity Read ↗

A FcɣRIIa polymorphism has a HLA-B57 and HLA-B27 independent effect on HIV disease outcome.Semantic proximity Read ↗

A common genetic variant in FCGR3A-V158F and risk of Kaposi sarcoma herpesvirus infection and classic Kaposi sarcoma.Semantic proximity Read ↗

Associations of classic Kaposi sarcoma with common variants in genes that modulate host immunity.Semantic proximity Read ↗

Risk of Classic Kaposi Sarcoma With Combinations of Killer Immunoglobulin-Like Receptor and Human Leukocyte Antigen Loci: A Population-Based Case-control Study.Semantic proximity Read ↗

Variant genotypes of the low-affinity Fcgamma receptors in two control populations and a review of low-affinity Fcgamma receptor polymorphisms in control and disease populations.Semantic proximity Read ↗

Fc-gamma receptor polymorphisms as predictive and prognostic factors in patients receiving oncolytic adenovirus treatment.Semantic proximity Read ↗

FcγR Genetic Variation and HIV-1 Vaccine Efficacy: Context And Considerations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.