Article

Variant genotypes of FcγRIIIA influence the development of Kaposi's sarcoma in HIV-infected men

2000-04-01

Abstract excerpt

Abstract Disturbances in inflammatory cytokine production and immune regulation coupled with human herpesvirus-8 (HHV-8) infection underlie the current understanding of the pathogenesis of Kaposi's sarcoma (KS), the most common HIV-associated malignancy. The low affinity Fc gamma receptors (FcγR) for IgG link humoral and cellular immunity by mediating interaction between antibodies and effector cells, such as phag...

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Literature Corpus work: 6c99909c-9544-572b-9f19-d8d911aaedec
DOI: 10.1182/blood.v95.7.2386

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