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Article

Interleukin-6 promoter polymorphism (-174 G/C) in Caucasian German patients with systemic lupus erythematosus

1 Apr 2001

Abstract excerpt

BACKGROUND: A biallelic polymorphism (--174 G/C) within the interleukin-6 (IL-6) promoter reportedly has functional importance through the modulation of IL-6 expression in vitro and in vivo. METHODS: We performed a population-based case-control study to analyse the association of the --174 G/C polymorphism with disease susceptibility and clinical manifestations in 211 German patients with systemic lupus...

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Share to Cytokine Signaling Pathways and Interactions
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PMID: 11312376
DOI: 10.1093/rheumatology/40.4.393

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