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Article

Regulation of centrosomes by the BRCA1-dependent ubiquitin ligase.

Cancer biology & therapy - 1 Oct 2008

Kais Zeina, Parvin Jeffrey D

Abstract excerpt

Centrosomes are the organelles that organize microtubule networks and establish the bipolar mitotic spindle, which is essential for the segregation of chromosomes during cell division. Proper duplication of centrosomes is necessary to prevent genetic instability, thus control of this organelle is...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18927495
DOI: 10.4161/cbt.7.10.7053
PMCID: PMC2628548

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-18927495-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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