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Article

Two efflux systems expressed simultaneously in multidrug-resistant Pseudomonas aeruginosa.

Antimicrobial agents and chemotherapy - 1 Oct 2000

Pumbwe L, Piddock L J

Abstract excerpt

Simultaneous overexpression of MexAB-OprM and MexEF-OprN was demonstrated for a multiply antibiotic-resistant clinical isolate of Pseudomonas aeruginosa (G49). G49 also had decreased expression of OprF. No mutations in mexR or its upstream promoter region, mexT, oprM, oprF, or sigX were revealed, suggesting regulation by a hitherto undescribed locus.

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Identifiers

PMID: 10991874
DOI: 10.1128/AAC.44.10.2861-2864.2000
PMCID: PMC90165

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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