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Article

A combined phenotypic and genotypic method for the detection of Mex efflux pumps in Pseudomonas aeruginosa.

The Journal of antimicrobial chemotherapy - 1 Mar 2007

Mesaros Narcisa, Glupczynski Youri, Avrain Laëtitia, Caceres Nancy E, Tulkens Paul M, Van Bambeke Françoise

Abstract excerpt

BACKGROUND: Mex efflux pumps contribute to multidrug resistance in Pseudomonas aeruginosa. Evidencing their expression in clinical isolates would help in rationalizing antibiotic selection. METHODS: We have developed a combined phenotypic and genotypic approach for the differential diagnosis of resistance mediated by four major transporters (MexAB-OprM, MexCD-OprJ, MexEF-OprN, MexXY-OprM). The methodology was...

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Source

Identifiers

PMID: 17289770
DOI: 10.1093/jac/dkl504

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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A combined phenotypic and genotypic method for the detection of Mex efflux pumps in Pseudomonas aeruginosa.PMID 17289770Read ↗

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Simultaneous overexpression of multidrug efflux pumps in Pseudomonas aeruginosa non-cystic fibrosis clinical isolates.Semantic proximity Read ↗

[Two efflux systems expressed simultaneously in clinical Pseudomonas aeruginosa].Semantic proximity Read ↗

Decoding MexB efflux pump genes: structural, molecular, and phylogenetic analysis of multidrug-resistant and extensively drug-resistant Pseudomonas aeruginosaSemantic proximity Read ↗

MexXY Multidrug Efflux System Is More Frequently Overexpressed in Ciprofloxacin Resistant French Clinical Isolates Compared to Hospital Environment OnesSemantic proximity Read ↗

MexXY RND pump of Pseudomonas aeruginosa PA7 effluxes bi-anionic β-lactams carbenicillin and sulbenicillin when it partners with the outer membrane factor OprA but not with OprMSemantic proximity Read ↗

Overexpression of MexAB-OprM efflux pump in carbapenem-resistant Pseudomonas aeruginosa.Semantic proximity Read ↗

MexXY multidrug efflux system of Pseudomonas aeruginosaSemantic proximity Read ↗

Resistance and virulence of Pseudomonas aeruginosa clinical strains overproducing the MexCD-OprJ efflux pump.Semantic proximity Read ↗

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