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Article

Efflux pump contribution to multidrug resistance in clinical isolates of Pseudomonas aeruginosa.

Pharmacotherapy - 1 Jul 2010

Kiser Tyree H, Obritsch Marilee D, Jung Rose, MacLaren Robert, Fish Douglas N

Abstract excerpt

STUDY OBJECTIVE: To determine if increased expression of efflux pumps, mutations in the genes encoding regulatory proteins for efflux pumps, or the combination is associated with multidrug-resistant (MDR) Pseudomonas aeruginosa isolates. DESIGN: Microbiologic evaluation of prospectively collected Pseudomonas aeruginosa isolates. SETTING: University teaching hospital. ISOLATES: One hundred eight unique P....

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PMID: 20575627
DOI: 10.1592/phco.30.7.632

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