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Article

Distribution of prion protein in the ileal Peyer's patch of scrapie-free lambs and lambs naturally and experimentally exposed to the scrapie agent.

The Journal of general virology - 1 Sept 2000

Heggebø Ragna, Press Charles McL, Gunnes Gjermund, Inge Lie Kai, Tranulis Michael A, Ulvund Martha, Groschup Martin H, Landsverk Thor

Abstract excerpt

A sensitive immunohistochemical procedure was used to investigate the presence of prion protein (PrP) in the ileal Peyer's patch of PrP-genotyped lambs, including scrapie-free lambs and lambs naturally and experimentally exposed to the scrapie agent. The tyramide signal amplification system was used to enhance the sensitivity of conventional immunohistochemical procedures to show that PrP was widely distributed...

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PMID: 10950992
DOI: 10.1099/0022-1317-81-9-2327

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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