Article
Distribution of the prion protein in sheep terminally affected with BSE following experimental oral transmission.
The Journal of general virology - 1 Oct 2001
Foster J D, Parnham D W, Hunter N, Bruce M
Abstract excerpt
This study has examined the distribution of PrP(Sc) in sheep by immunocytochemistry of tissues recovered from terminally affected animals following their experimental infection by the oral route with BSE. Despite a wide range of incubation period lengths, affected sheep showed a similar distribution of high levels of PrP(Sc) throughout the central nervous system. PrP(Sc) was also found in the lymphoid system,...
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