Article
Detection of PrPSc in lymphoid tissues of lambs experimentally exposed to the scrapie agent.
Journal of comparative pathology - 1 Jan 2000
Heggebø R, Press C McL, Gunnes G, Ulvund M J, Tranulis M A, Lsverk T
Abstract excerpt
Histoblotting and immunohistochemistry were used to detect disease-associated prion protein (PrP(Sc)) in lymphoid tissues of lambs of known PrP genotype infected with the scrapie agent by stomach tube at the age of 2 months. The ileal and jejunal Peyer's patches and retropharyngeal and distal jejunal lymph nodes were studied 1 week, 5 weeks, 5 months and 11 months after inoculation. Other lymphoid tissues...
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