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Article

Promotion of hepatocarcinogenesis by phenobarbital in c-myc/TGF-alpha transgenic mice.

Molecular carcinogenesis - 1 Jul 2000

Sanders S, Thorgeirsson S S

Abstract excerpt

Previous work has shown that phenobarbital (PB) can promote cell survival in double transgenic c-myc/transforming growth factor (TGF)-alpha mice. This was achieved through a suppression of cell death brought about, at least in part, by a general increase in the level of bcl-2 protein and a decrease in TGF-beta1 in treated versus untreated animals. No changes were found in TGF-beta type II receptor or in bcl-X(L)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 10942533
DOI: 10.1002/1098-2744(200007)28:3<168::aid-mc5>3.0.co;2-e

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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