Article
Altered bcl-2 family expression during non-genotoxic hepatocarcinogenesis in mice.
Carcinogenesis - 1 Aug 1999
Christensen J G, Romach E H, Healy L N, Gonzales A J, Anderson S P, Malarkey D E, Corton J C, Fox T R, Cattley R C, Goldsworthy T L
Abstract excerpt
Dysregulation of apoptosis is an important component of multistage hepatocarcinogenesis. Members of the bcl-2 protein family are important in the regulation of apoptosis and their expression is altered in several cancers. The objectives of the present study were to determine whether the expression of members of the bcl-2 protein family are altered in mouse liver during acute treatment with non-genotoxic...
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