Article
Modulation of virulence genes by the two-component system PhoP-PhoQ in avian pathogenic Escherichia coli.
Polish journal of veterinary sciences - 1 Jan 2016
Tu Jian, Huang Boyan, Zhang Yu, Zhang Yuxi, Xue Ting, Li Shaocan, Qi Kezong
Abstract excerpt
Avian pathogenic Escherichia coli (APEC) infections are a very important problem in the poultry industry. PhoP-PhoQ is a two-component system that regulates virulence genes in APEC. In this study, we constructed strains that lacked the PhoP or PhoQ genes to assess regulation of APEC pathogenicity by the PhoP-PhoQ two-component system. The PhoP mutant strain AE18, PhoQ mutant strain AE19, and PhoP/PhoQ mutant...
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