Identification of a mutation in the pst-phoU operon that reduces pathogenicity of an Escherichia coli strain causing septicemia in pigs.

doi:10.1128/iai.63.12.4924-4927.1995

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Article

Identification of a mutation in the pst-phoU operon that reduces pathogenicity of an Escherichia coli strain causing septicemia in pigs.

Infection and immunity - 1 Dec 1995

Daigle F, Fairbrother J M, Harel J

Abstract excerpt

We used transposon (TnphoA) mutagenesis to study the role of virulence factors of pathogenic Escherichia coli strains associated with septicemia in calves and piglets. We have produced an avirulent and serum-sensitive mutant of wild-type pathogenic strain 5131 O115:K"V165":F165 and have localized and identified the TnphoA insertion in the pstC gene of the pst-phoU operon. This operon encodes the PstSCAB...

Topics

Animals
Bacterial Proteins
Base Sequence
Cloning, Molecular
DNA Primers
DNA Transposable Elements
Escherichia coli
Escherichia coli Infections
Escherichia coli Proteins
Membrane Transport Proteins
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Operon

Sepsis

Swine

Swine Diseases

Transcription Factors

Virulence

Source

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Identifiers

PMID: 7591158
DOI: 10.1128/iai.63.12.4924-4927.1995
PMCID: PMC173707

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7591158-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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