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Article

Alterations of the PPP2R1B gene located at 11q23 in human colorectal cancers

1 Aug 2000

Abstract excerpt

BACKGROUND/AIMS: In 1998 the PPP2R1B gene encoding the A subunit of the serine/threonine protein phosphatase was identified as a putative tumour suppressor gene in lung and colon cancer in the chromosome region 11q22-24. The aim of the present study was to determine the type of alterations in primary rectal cancers as well as colon cancers and the correlation between these alterations and clinicopathological...

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PMID: 10896920
DOI: 10.1136/gut.47.2.268

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