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A Role for the β Isoform of Protein Kinase C in Fear Conditioning

15 Aug 2000

Abstract excerpt

The protein kinase C family of enzymes has been implicated in synaptic plasticity and memory in a wide range of animal species, but to date little information has been available concerning specific roles for individual isoforms of this category of kinases. To investigate the role of the beta isoform of PKC in mammalian learning, we characterized mice deficient in the PKC beta gene using anatomical, biochemical,...

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PMID: 10934237
DOI: 10.1523/jneurosci.20-16-05906.2000

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