Article
Mice lacking PKC gamma exhibit decreased anxiety.
Behavior genetics - 1 Mar 2000
Bowers B J, Collins A C, Tritto T, Wehner J M
Abstract excerpt
To investigate the contribution of the PKC gamma isoform of protein kinase C (PKC) in neurochemical pathways regulating anxiety, mice lacking the gene encoding PKC gamma were tested with heterozygote and wild-type littermates in three approach-avoidance tests of anxiety. Null mutant mice consiste...
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