Article
Interaction between the small GTPase Ran/Gsp1p and Ntf2p is required for nuclear transport.
Molecular and cellular biology - 1 Jul 1997
Wong D H, Corbett A H, Kent H M, Stewart M, Silver P A
Abstract excerpt
Bidirectional movement of proteins and RNAs across the nuclear envelope requires Ran, a Ras-like GTPase. A genetic screen of the yeast Saccharomyces cerevisiae was performed to isolate conditional alleles of GSP1, a gene that encodes a homolog of Ran. Two temperature-sensitive alleles, gsp1-1 and...
Topics
- Amino Acid Sequence
- Biological Transport
- Carrier Proteins
- Cell Nucleus
- Fungal Proteins
- GTP-Binding Proteins
- Macromolecular Substances
- Molecular Sequence Data
- Monomeric GTP-Binding Proteins
- Mutation
- Nuclear Envelope
- Nuclear Proteins
- Nucleocytoplasmic Transport Proteins
- Protein Binding
- Saccharomyces cerevisiae