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Article

MSH4 acts in conjunction with MLH1 during mammalian meiosis

1 Aug 2000

Abstract excerpt

MSH4 is a meiosis-specific MutS homolog. In yeast, it is required for reciprocal recombination and proper segregation of homologous chromosomes at meiosis I. MLH1 (MutL homolog 1) facilitates both mismatch repair and crossing over during meiosis in yeast. Germ-line mutations in the MLH1 human gene are responsible for hereditary nonpolyposis cancer, but the analysis of MLH1-deficient mice has revealed that MLH1 is...

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PMID: 10928988
DOI: 10.1096/fj.99-0851com

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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MSH4 acts in conjunction with MLH1 during mammalian meiosisPMID 10928988Read ↗

MSH4 acts in conjunction with MLH1 during mammalian meiosisSemantic proximity Read ↗

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