MSH5, a novel MutS homolog, facilitates meiotic reciprocal recombination between homologs in Saccharomyces cerevisiae but not mismatch repair.

doi:10.1101/gad.9.14.1728

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Article

MSH5, a novel MutS homolog, facilitates meiotic reciprocal recombination between homologs in Saccharomyces cerevisiae but not mismatch repair.

Genes & development - 15 Jul 1995

Hollingsworth N M, Ponte L, Halsey C

Abstract excerpt

Using a screen designed to identify yeast mutants specifically defective in recombination between homologous chromosomes during meiosis, we have obtained new alleles of the meiosis-specific genes, HOP1, RED1, and MEK1. In addition, the screen identified a novel gene designated MSH5 (MutS Homolog 5). Although Msh5p exhibits strong homology to the MutS family of proteins, it is not involved in DNA mismatch repair....

Topics

Alleles
Amino Acid Sequence
Base Sequence
Chromosome Mapping
Cloning, Molecular
Crossing Over, Genetic
DNA Repair
DNA, Fungal
Fungal Proteins
Gene Conversion
Genes, Fungal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Meiosis

Mitosis

Molecular Sequence Data

Mutation

Recombination, Genetic

Saccharomyces cerevisiae

Saccharomyces cerevisiae Proteins

Source

Open in PubMed

Identifiers

PMID: 7622037
DOI: 10.1101/gad.9.14.1728

Genes

MSH5
MSH4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7622037-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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MSH5, a novel MutS homolog, facilitates meiotic reciprocal recombination between homologs in Saccharomyces cerevisiae but not mismatch repair.PMID 7622037Read ↗

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