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Article

Structural basis for the functional difference between Smad2 and Smad3 in FAST-2 (forkhead activin signal transducer-2)-mediated transcription.

The Biochemical journal - 15 Aug 2000

Nagarajan R P, Chen Y

Abstract excerpt

Smad2 and Smad3 are signalling proteins that are involved in mediating the transcriptional regulation of target genes downstream of transforming growth factor-beta and activin receptors. Although they are structurally very similar, Smad2 and Smad3 have some functional differences in transducing signals for these receptors. In FAST-2 (forkhead activin signal transducer-2)-mediated transcriptional regulation using...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 10926851
PMCID: PMC1221249

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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