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Article

Identification of Smad2, a Human Mad-related Protein in the Transforming Growth Factor β Signaling Pathway

1 Jan 1997

Abstract excerpt

Transforming growth factor-beta (TGF-beta) superfamily members are multifunctional cytokines that exert their effects via heteromeric complexes of two distinct serine and threonine kinase receptors. Drosophila mothers against decapentaplegic and related genes in Caenorhabditis elegans, Xenopus, and mammals were shown to function downstream in the intracellular signaling pathways of TGF-beta superfamily members....

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PMID: 9006934
DOI: 10.1074/jbc.272.5.2896

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