Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cell volume-dependent phosphorylation of proteins of the cortical cytoskeleton and cell-cell contact sites. The role of Fyn and FER kinases.

The Journal of biological chemistry - 13 Oct 2000

Kapus A, Di Ciano C, Sun J, Zhan X, Kim L, Wong T W, Rotstein O D

Abstract excerpt

Cell volume affects diverse functions including cytoskeletal organization, but the underlying signaling pathways remained undefined. We have shown previously that shrinkage induces Fyn-dependent tyrosine phosphorylation of the cortical actin-binding protein, cortactin. Because FER kinase was implicated in the direct phosphorylation of cortactin, we investigated the osmotic responsiveness of FER and its...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adherens Junctions
Share to alpha Catenin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Catenins

Share to Delta Catenin

Share to Intercellular Junctions

Share to Osmolar Concentration

Share to Osmotic Pressure

Share to Proto-Oncogene Proteins c-fyn

Source

Identifiers

PMID: 10921917
DOI: 10.1074/jbc.M003172200

Genes

FER

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cell volume-dependent phosphorylation of proteins of the cortical cytoskeleton and cell-cell contact sites. The role of Fyn and FER kinases.PMID 10921917Read ↗

Unveiling the Intricate Connection: Cell Volume as a Key Regulator of MechanotransductionSemantic proximity Read ↗

Continuous association of cadherin with beta-catenin requires the non-receptor tyrosine-kinase Fer.Semantic proximity Read ↗

Hyperosmotic stress induces rapid focal adhesion kinase phosphorylation at tyrosines 397 and 577. Role of Src family kinases and Rho family GTPases.Semantic proximity Read ↗

Identification of Fer tyrosine kinase localized on microtubules as a platelet endothelial cell adhesion molecule-1 phosphorylating kinase in vascular endothelial cells.Semantic proximity Read ↗

Kinase-dependent adhesion to fibronectin: regulation by calreticulin.Semantic proximity Read ↗

SPIN90 dephosphorylation is required for cofilin-mediated actin depolymerization in NMDA-stimulated hippocampal neurons.Semantic proximity Read ↗

Osmotic stimulation of the Na+/H+ exchanger NHE1: relationship to the activation of three MAPK pathways.Semantic proximity Read ↗

Osmotic stress-mediated activation of RET kinases involves intracellular disulfide-bonded dimer formation.Semantic proximity Read ↗

Hyperosmotic stress induces Rho/Rho kinase/LIM kinase-mediated cofilin phosphorylation in tubular cells: key role in the osmotically triggered F-actin response.Semantic proximity Read ↗

Actin-based cytoskeleton regulates a chloride channel and cell volume in a renal cortical collecting duct cell line.Semantic proximity Read ↗

Aquaporin 1 mediates early responses to osmotic stimuli in endothelial cells via the calmodulin pathway.Semantic proximity Read ↗

The role of tyrosine phosphorylation of cortactin in the locomotion of endothelial cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.