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Article

Aquaporin 1 mediates early responses to osmotic stimuli in endothelial cells via the calmodulin pathway.

FEBS open bio - 1 Jan 2021

Jiang Yong, Wang Chengqi, Ma Rui, Zhao Ying, Ma Xinyue, Wan Jiaxin, Li Chunxiang, Chen Fanghao, Fang Fang, Li Mingguang

Abstract excerpt

The aquaporins (AQPs) are a family of integral membrane proteins which play critical roles in controlling transcellular water movement in various tissues throughout the body. AQP1 helps mediate the cellular response to osmotic stress and tissue water permeability. However, the mechanism by which AQP1 mediates changes in cell volume is not completely clear. Here, we investigated how AQP1 responds to and controls...

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Identifiers

PMID: 33125833
DOI: 10.1002/2211-5463.13020
PMCID: PMC7780103

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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