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Article

Properties of HLA class II molecules divergently associated with Goodpasture's disease.

International immunology - 1 Aug 2000

Phelps R G, Jones V, Turner A N, Rees A J

Abstract excerpt

Goodpasture's disease provides an opportunity to analyse molecular mechanisms that may underlie MHC class II associations with autoimmune disease because it is caused by autoimmunity to a defined antigen [the 230 amino acid NC1 domain of the alpha3 chain of type IV collagen (alpha3(IV)NC1)] and has strong HLA class II associations. We compared the alpha3(IV)NC1 peptide binding of class II molecules with strong...

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PMID: 10917888
DOI: 10.1093/intimm/12.8.1135

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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