Article
Molecular analysis of HLA class II genes in Goodpasture's disease.
QJM : monthly journal of the Association of Physicians - 1 Feb 1995
Burns A P, Fisher M, Li P, Pusey C D, Rees A J
Abstract excerpt
A molecular analysis of HLA class II genes was undertaken in order to characterize the previously reported association between HLA-DR2 and glomerulonephritis caused by antibodies to glomerular basement membrane (Goodpasture's disease). Genomic DNA was prepared from 53 patients with Goodpasture's disease and analysed by: (i) Southern blotting using cDNA probes to DRB, DQA and DQB genes, after digestion with TaqI...
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