Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Biochemical and molecular analyses of the Streptococcus pneumoniae acyl carrier protein synthase, an enzyme essential for fatty acid biosynthesis.

The Journal of biological chemistry - 6 Oct 2000

McAllister K A, Peery R B, Meier T I, Fischl A S, Zhao G

Abstract excerpt

Acyl carrier protein synthase (AcpS) is an essential enzyme in the biosynthesis of fatty acids in all bacteria. AcpS catalyzes the transfer of 4'-phosphopantetheine from coenzyme A (CoA) to apo-ACP, thus converting apo-ACP to holo-ACP that serves as an acyl carrier for the biosynthesis of fatty acids and lipids. To further understand the physiological role of AcpS, we identified, cloned, and expressed the acpS...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acyl Carrier Protein
Share to Binding, Competitive

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromatography, Gel

Share to Coenzyme A

Share to Cross-Linking Reagents

Share to Streptococcus pneumoniae

Share to Transferases (Other Substituted Phosphate Groups)

Share to Ultracentrifugation

Source

Identifiers

PMID: 10903317
DOI: 10.1074/jbc.M004475200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Biochemical and molecular analyses of the Streptococcus pneumoniae acyl carrier protein synthase, an enzyme essential for fatty acid biosynthesis.PMID 10903317Read ↗

The enigmatic acyl carrier protein phosphodiesterase of Escherichia coli: genetic and enzymological characterization.Semantic proximity Read ↗

A Single Mutation in the "DSL" Motif of the Acyl Carrier Protein Can Prevent Its In Vivo Phosphopantetheinylation by E. coli Holo-Acyl Carrier Protein Synthase (AcpS).Semantic proximity Read ↗

Structural Comparison of Acinetobacter baumannii β-ketoacyl-acyl Carrier Protein Reductases in Fatty Acid and Aryl Polyene BiosynthesisSemantic proximity Read ↗

Functional characterization of the acyl carrier protein (PfACP) and beta-ketoacyl ACP synthase III (PfKASIII) from Plasmodium falciparum.Semantic proximity Read ↗

Topology and active site of PlsY: the bacterial acylphosphate:glycerol-3-phosphate acyltransferase.Semantic proximity Read ↗

Acyl-AcpB, a FabT co-repressor in <i>Streptococcus pyogenes</i>Semantic proximity Read ↗

Transcriptional regulation of fatty acid biosynthesis in Streptococcus pneumoniae.Semantic proximity Read ↗

Expression, purification, characteristics and homology modeling of the HMGS from Streptococcus pneumoniae.Semantic proximity Read ↗

Highly conserved nucleotide phosphatase essential for membrane lipid homeostasis in Streptococcus pneumoniae.Semantic proximity Read ↗

Metabolic basis for the differential susceptibility of Gram-positive pathogens to fatty acid synthesis inhibitors.Semantic proximity Read ↗

Genetic characterization of pcpS, encoding the multifunctional phosphopantetheinyl transferase of Pseudomonas aeruginosa.Semantic proximity Read ↗

Catalysis and mechanism of malonyl transferase activity in type II fatty acid biosynthesis acyl carrier proteins.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.