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Article

Topology and active site of PlsY: the bacterial acylphosphate:glycerol-3-phosphate acyltransferase.

The Journal of biological chemistry - 13 Apr 2007

Lu Ying-Jie, Zhang Fan, Grimes Kimberly D, Lee Richard E, Rock Charles O

Abstract excerpt

The most widely distributed biosynthetic pathway to initiate phosphatidic acid formation in bacterial membrane phospholipid biosynthesis involves the conversion of acyl-acyl carrier protein to acylphosphate by PlsX and the transfer of the acyl group from acylphosphate to glycerol 3-phosphate by an integral membrane protein, PlsY. The membrane topology of Streptococcus pneumoniae PlsY was determined using the...

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PMID: 17308305
DOI: 10.1074/jbc.M700374200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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