Article
Catalysis and mechanism of malonyl transferase activity in type II fatty acid biosynthesis acyl carrier proteins.
Molecular bioSystems - 1 Jun 2009
Misra Ashish, Surolia Namita, Surolia Avadhesha
Abstract excerpt
One of the unexplored, yet important aspects of the biology of acyl carrier proteins (ACPs) is the self-acylation and malonyl transferase activities dedicated to ACPs in polyketide synthesis. Our studies demonstrate the existence of malonyl transferase activity in ACPs involved in type II fatty acid biosynthesis from Plasmodium falciparum and Escherichia coli. We also show that the catalytic malonyl transferase...
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