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Functional characterization of the acyl carrier protein (PfACP) and beta-ketoacyl ACP synthase III (PfKASIII) from Plasmodium falciparum.

Molecular and biochemical parasitology - 28 Aug 2002

Waters Norman C, Kopydlowski Karen M, Guszczynski Tadeusz, Wei Lan, Sellers Patrice, Ferlan Jill T, Lee Patricia J, Li Zhiyu, Woodard Cassandra L, Shallom Shamira, Gardner Malcolm J, Prigge Sean T

Abstract excerpt

The genome of the malaria parasite, Plasmodium falciparum, appears to contain the proteins necessary for a Type II dissociated fatty acid biosynthetic system. Here we report the functional characterization of two proteins from this system. Purified recombinant acyl carrier protein (ACP) and beta-ketoacyl-ACP synthase III (KASIII) from P. falciparum are soluble and active in a truncated form. Malarial ACP is...

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PMID: 12270624
DOI: 10.1016/s0166-6851(02)00140-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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