Article
Highly conserved nucleotide phosphatase essential for membrane lipid homeostasis in Streptococcus pneumoniae.
Molecular microbiology - 1 Jul 2016
Kuipers Kirsten, Gallay Clement, Martínek Václav, Rohde Manfred, Martínková Markéta, van der Beek Samantha L, Jong Wouter S P, Venselaar Hanka, Zomer Aldert, Bootsma Hester, Veening Jan-Willem, de Jonge Marien I
Abstract excerpt
Proteins belonging to the DHH family, a member of the phosphoesterase superfamily, are produced by most bacterial species. While some of these proteins are well studied in Bacillus subtilis and Escherichia coli, their functions in Streptococcus pneumoniae remain unclear. Recently, the highly conserved DHH subfamily 1 protein PapP (SP1298) has been reported to play an important role in virulence. Here, we provide...
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