Article
Association of early osteoarthritis of the knee with a Taq I polymorphism of the vitamin D receptor gene.
Arthritis and rheumatism - 1 Aug 1997
Keen R W, Hart D J, Lanchbury J S, Spector T D
Abstract excerpt
OBJECTIVE: To determine whether a polymorphism of the vitamin D receptor (VDR) gene, already associated with osteoporosis, might also relate to the risk of osteoarthritis (OA). METHODS: A population cohort of 351 postmenopausal women (ages 45-64 years) was studied using anteroposterior radiographs of the knee, which were graded for OA according to the Kellgren and Lawrence classification system. The VDR genotype...
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