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Article

Vitamin D receptor genotype is associated with radiographic osteoarthritis at the knee.

The Journal of clinical investigation - 15 Jul 1997

Uitterlinden A G, Burger H, Huang Q, Odding E, Duijn C M, Hofman A, Birkenhäger J C, van Leeuwen J P, Pols H A

Abstract excerpt

Osteoporosis and osteoarthritis are age-related disorders of the skeleton with genetic components. Low bone density is a risk factor for osteoporotic fracture while osteoarthritis is associated with increased bone density. The 1,25-dihydroxyvitamin D3 receptor (VDR) gene locus was previously foun...

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Identifiers

PMID: 9218501
DOI: 10.1172/JCI119530
PMCID: PMC508187

Genes

VDR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-9218501-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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