Article
A genetic association study of the IGF-1 gene and radiological osteoarthritis in a population-based cohort study (the Rotterdam Study).
Annals of the rheumatic diseases - 1 Jun 1998
Meulenbelt I, Bijkerk C, Miedema H S, Breedveld F C, Hofman A, Valkenburg H A, Pols H A, Slagboom P E, van Duijn C M
Abstract excerpt
OBJECTIVE: A genetic association study was performed to investigate whether radiographical osteoarthritis (ROA) was associated with specific genotypes of the insulin-like growth factor I (IGF-1) gene. METHODS: Subjects aged 55-65 years were selected from a population-based study of which ROA at t...
Topics
- Aged
- Alleles
- Body Mass Index
- Bone Density
- Female
- Genotype
- Humans
- Insulin-Like Growth Factor I
- Male
- Middle Aged
- Osteoarthritis
- Prospective Studies
- Radiography