Lack of association between osteoarthritis of the hip and gene polymorphisms of VDR, COL1A1, and COL2A1 in postmenopausal women.

doi:10.1002/1529-0131(199811)41:11<1946::AID-ART8>3.0.CO;2-Z

Back to search

Article

Lack of association between osteoarthritis of the hip and gene polymorphisms of VDR, COL1A1, and COL2A1 in postmenopausal women.

Arthritis and rheumatism - 1 Nov 1998

Aerssens J, Dequeker J, Peeters J, Breemans S, Boonen S

Abstract excerpt

OBJECTIVE: To evaluate whether DNA polymorphisms of the VDR (vitamin D receptor), COL1A1 (alpha1 type I collagen), and COL2A1 (alpha1 type II collagen) genes, which have previously been linked to bone mineral density (BMD) and/or osteoarthritis (OA), are also associated with OA of the hip (OAH)....

Topics

Aged
Aged, 80 and over
Belgium
Collagen
Female
Gene Frequency
Genotype
Humans
Osteoarthritis, Hip
Polymorphism, Genetic
Postmenopause
Procollagen
Receptors, Calcitriol
Transcriptional Activation

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.