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Article

Estrogen receptor alpha gene haplotype is associated with radiographic osteoarthritis of the knee in elderly men and women.

Arthritis and rheumatism - 1 Jul 2003

Bergink Arjan P, van Meurs Joyce B, Loughlin John, Arp Pascal P, Fang Yue, Hofman Albert, van Leeuwen Johannes P T M, van Duijn Cornelia M, Uitterlinden André G, Pols Huibert A P

Abstract excerpt

OBJECTIVE: Genetic influences have been shown to play an important role in the etiology of osteoarthritis (OA), but the genes involved are ill-defined. We studied the association between polymorphisms in the estrogen receptor alpha (ERalpha) gene and the prevalence of radiographic OA of the knee....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12847685
DOI: 10.1002/art.11046

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-12847685-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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